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Synthesis, Characterization and Antimicrobial Study Of Mixed Isoniazid
8 páginas
Publicado por
Alexander Decker
Chemistry and Materials Research www.
iiste.
org
ISSN 2224- 3224 (Print) ISSN 2225- 0956 (Online)
Vol 2, No.
3, 2012
1
Synthesis, Characterization and Antimicrobial Study Of Mixed
Isoniazid-Trimethoprim Metal Drug Complexes
Bamigboye M....
[Mais]
Chemistry and Materials Research www.
iiste.
org
ISSN 2224- 3224 (Print) ISSN 2225- 0956 (Online)
Vol 2, No.
3, 2012
1
Synthesis, Characterization and Antimicrobial Study Of Mixed
Isoniazid-Trimethoprim Metal Drug Complexes
Bamigboye M.
O*1
, Obaleye J.
A1
Lawal M2
.
and Aluko O.
M1
.
1.
Department of Chemistry, University of Ilorin, Ilorin, Kwara State, Nigeria.
2.
Kebbi State, University of Science and Technology.
Aliereo Kebbi State.
Department of Pure and Applied
Chemistry.
Email: seymercyx@yahoo.
com
ABSTRACT
The Mn2+
, Fe2+
, Cu2+
, Co2+
, Zn2+
, Cd2+
complexes of mixed of Trimethoprim- Isoniazid were synthesized.
The
complexes were characterized using solubility, melting point, conductivity measurement and infrared
spectroscopy.
Trimethoprim complexes of coordination of the metal to the ligands is through the nitrogen of the
pyrimidine group and coordination through the nitrogen of the amine group.
The antimicrobial activity of the
complexes were carried out against St
[Menos]
Tags
activity,
antimicrobial,
chemistry,
complexes,
conductivity,
infrared,
isoniazid,
issn,
ligands,
materials,
melting,
metal,
mixed,
obtained,
point,
synthesis,
trimethoprim
